Open Access
Table 1
Clinical characteristics of the enrolled subjects.
| Parameters | CHB (n = 30) | CHB with ETV (n = 30) | Control (n = 20) | P value |
|---|---|---|---|---|
| Male/Female | 20/10 | 18/12 | 14/6 | |
| Age (year) | 45 ± 8.2 | 45 ± 12.7 | 43 ± 8.2 | 0.351 |
| ALT (IU/L) | 237 ± 96.8* | 20 ± 4.2 | 18.3 ± 3.8 | <0.0001 |
| Total bilirubin (mg/dL) | 1.75 ± 0.9* | 0.7 ± 0.32 | 0.6 ± 0.3 | <0.0001 |
| INR | 1.1 ± 0.2 | 1,12 ± 0.23 | 1 ± 0.09 | 0.108 |
| WBC count (×103/uL) | 6.8 ± 1.7 | 7.3 ± 2.3 | 6.9 ± 2 | 0.923 |
| HBV DNA( log10 copies/mL) (P/N) | 8.3 ± 4.5 | <LOD (4/26) | ND | |
| HBsAg (positive/negative) | 30/0 | 27/3 | ND | |
| HBeAg (positive/negative) | 6/24 | 7/23 | ND | |
| Anti-HBe Ab (positive/negative) | 24/6 | 23/7 | ND | |
| Prior medication for HBV | 0 | ETV | 0 |