Original Article

The effectiveness of mineralized plasmatic matrix in the closure of alveolar clefts with volumetric assessment

Department of Oral and Maxillofacial Surgery, Panineeya Institute of Dental Sciences and Research Centre, Kamal Nagar, Dilshukhnagar −500060, Hyderabad, Telangana State, India

^* Corresponding author: dr.e.p.omfs@gmail.com

Received: 14 May 2021
Accepted: 15 June 2021

Abstract

Objectives: The purpose of this study is to assess the effectiveness of mineralized plasmatic matrix in the soft tissue closure of naso-alveolar fistula, to estimate the postoperative bone fill and volume of the graft placed in the alveolar cleft defect using cone-beam computed tomography (CBCT) at 3rd- month and 6th- month. Material and methods: 10 patients, in the age group of 15‑30 years were included in this study. They were diagnosed with unilateral cleft lip and alveolus defects with or without a cleft palate requiring late secondary alveolar bone grafting. Alveolar cleft defects were closed with mineralized plasmatic matrix (MPM), a combination of autogenous iliac bone graft and platelet rich plasma (PRP) and platelet rich fibrin (PRF). Results: The mean defect volume pre-operatively is 0.75 cm³ and at the end of 3rd-month postoperatively is 0.51 cm³ and at 6th-month postoperatively is 0.27 cm³. The average percentage of bone fill between preoperative (A) & 3th- month postoperatively (B) is 33.4% and between 3rd-month (B) and 6th-month post operatively (C) is 49.5%. Conclusions: Utilization of this new matrix (MPM), has shown to be effective in the closure of the cleft defect, oro-nasal fistula and also reduction in the volume of the residual cleft defect seen with sequential cone-beam computed tomography (CBCT) radiographs.