Open Access

Table 2

Characteristics of patients included in the study and wound evolution before and after CACIPLIQ20 treatment. M, male; F, female; F, fibrin; G, granulation tissue; SR, surface reduction; RF, right foot.

Case # Age, years, sex Ulcer location Ulcer duration Ulcer size at baseline (cm2) Aspect at baseline Appearance after 4 weeks % SR after 2 weeks % SR after 4 weeks % SR after 8 weeks Healing after 12 weeks Commments Follow up (months) Alive at last follow up
1 87M Foot, medial aspect 12 0.5 100%F 90%G 10%F 0% 0% 49% Stopped Left the study after 8 weeks, AHT Lost to follow up
2 86F Foot, medial edge 6 0.45 100%F 20%F 80%G 44% 44% 80% Healed Hypertension, myocardial infarction, AHT 24 Yes
2 86F Heel 6 1.05 30%F 70%G Healed 100% 100% 100% Healed Yes
3 85F Left, medial aspect 10 9.1 10%F 90%G 90%G 10%F 0% 0% 23% Stopped Bacterial infection between 4 and 8 weeks HTA healed later 24 Yes
4 83M Foot, sole 2 5.6 30%F 70%G 100%G 4% 36% 49% Not healed Renal dialysis, died months after study completion from unrelated causes, HTA 16 Yes
5 88M Big toe, lateral aspect >18 0.99 100%F 70%F 30%G 19% 0% 0% Not healed Died from cachexia, HTA, smoker 2 No
6 93F Lateral malleolus 4 73.8 20%F 80%G 95%G 13% 13% 27% Healed other slowly healing ulcers, HTA Lost to follow up
7 74M Foot, lateral edge >12 2.4 100%G 100%G 37% 62% 100% Healed 24 Yes
8 63M Heel 7 0.7 20%F 80%G 100%G 14% 29% −50% Not healed Bacterial infection, bladder carcinoma, HTA 24 Yes
9 62M Stump ulcer 1 49 20%F 100%G 11% 46% 100% Healed Diabetes 12 Yes
9 62M 2 weeks after femoral amputation 15 80%G 0% 78% 100% Healed 12 Yes
10 89F >12 0.6 50%F 50%G 100%G 0% 40% 100% Healed HTA Lost to follow up
11 78M 1 41.2 90%G 0% 24% 56% Not healed 24 Yes
12 62M 2 24 30% SR stopped the treatment 20% 13% NA Not healed Amputation of 4 toes 3 months later then healed with CACIPLIQ20® (outof the study), HTA, diabetes, smoker 24 Yes
Total 1 healed, remain 13 5 healed remain 12 7 healed remain 7 8 alive

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