Evolution of analgesic consumption over the treatment period. (a) Evolution of the analgesic class over the treatment period. The majority of patients at T0 were taking class 3 (striped bars) analgesics at T0, which decreased over the course of the treatment. (b) Overall analgesic consumption decreased over time, calculated by the sum of the patients of the analgesic class multiplied by the corresponding arbitrary unit (none = 0 AU, class 1 = 1 AU, class 2 = 2AU, class 3 = 3AU). AU, arbitrary unit.